Covid-19 is dangerous not only due to the direct effects on the health of the infection but also other diseases and symptoms. In addition to the physiological risks, infertility, cUniversity of Washington researchers received Covid-19 was found to be able to enter the brain because it carries a protein capable of crossing the barrier in the spinal cord.
They discovered the mutant protein that viruses use to attach to human cells, can cross the blood-brain barrier in mice and believe that the same process could happen in humans. This makes sense when explaining some of the unusual symptoms of Covid-19 patients, such as headache, brain fog, and even seizures.
Patients with Covid-19 may experience brain and nerve health problems such as a memory disorder, even after recovery.
When a person is infected with Covid-19, their immune system targets and attacks mutant proteins, which can cause inflammation because sometimes healthy tissues are damaged in the process. Covid-19 usually attacks the lungs and airways, which is why the most common symptoms are coughing and difficulty breathing and patients with a serious medical condition require a ventilator.
However, researchers at the University of Washington believe that the mutant proteins also penetrate the brain in some patients and cause inflammation. They warn that nerve damage can last for a very long time. This is not a new phenomenon as many HIV patients also have similar cognitive problems caused by a protein released by the virus.
The blood-brain barrier is a tightly packed layer of cells located between the blood vessels in the brain and spinal cord. It acts as a filter between the organ and the rest of the body, allowing only essential nutrients to pass through and removing toxins and many pathogens.
The similarities between HIV and Covid-19 in the brain are “like déjà vu”, said lead researcher William Banks, a professor of medicine at the University of Washington.dementia or hallucinogenic memory).
He added: “The spike in S1 protein is likely to cause the brain to secrete cytokines and cause inflammation. We know that with Covid-19, the patient will have difficulty breathing due to lung infection, but with additional explanation “It is a virus that gets into the brain’s respiratory center, thereby causing these problems. Many of the bad effects this virus causes can be very severe, lasting because it enters the brain”.
The study, published in the journal Nature Neuroscience, explains why so many patients with even mild illnesses feel fatigued months after they recover.
Banks and colleagues focus on the blood brain barrier and its role in Alzheimer’s disease, obesity, diabetes and HIV. They then focused their full efforts on the mutagenic protein of the SARS-CoV-2 virus.
Mild inflammation can occur as the body fights any viral infection, including Covid-19. But in some people, especially the elderly and those with an underlying health condition, their immune systems fail while trying to get rid of the virus from the body.
Cyclone cytokines are thought to be one of the most common causes of death during the Covid-19 pandemic, causing damage to the heart, liver and kidneys. This is Deadly complications have shown that immune molecules also begin to attack healthy tissues. Abnormal blood clotting, heart attack and stroke, were also assessed as the cause of significant death in Covid-19 patients. There is no clear figure of the proportion of hospitalized patients who have experienced a cytokine storm.
Experts have warned of serious neurological consequences associated with long-term damage to the brain and nerves caused by Covid-19. A UK-wide alliance has a name CoroNerve – Covid-19 National Monitoring Program for Neurological Complications, has been set up to track such cases. It is overseen by both the British Association of Neuroscientists and the Royal College of Psychiatry.
Huong Giang (Source: dailymail)